BCL2 Gene - Gene. Cards | BCL2 Protein. This gene encodes an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Alternative splicing results in multiple transcript variants. Ref. Seq, Feb 2. 01. BCL2 (BCL2, Apoptosis Regulator) is a Protein Coding gene. Diseases associated with BCL2 include Follicular Lymphoma 1 and Follicular Lymphoma. Among its related pathways are PEDF Induced Signaling and Validated targets of C- MYC transcriptional repression. GO annotations related to this gene include protein homodimerization activity and identical protein binding. Lyberty.com's weekly/monthly splash page. (Yes, a splash page is old fashioned, but it's been a tradition here since 1999.). BCL2 (BCL2, Apoptosis Regulator) is a Protein Coding gene. Diseases associated with BCL2 include Follicular Lymphoma 1 and. An important paralog of this gene is BCL2. L1. Suppresses apoptosis in a variety of cell systems including factor- dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. 68 4 4 12/28/2014 2012 6 110 11 23293587. 37 30 30 12/27/2014 2012 367 26 2495 2504 10 23268664. 13 0 0 12/21/2014 2012 137 23 234108 6 23267472. 127 5 5 12/20/2014. YELYItFFyuV free bf2 1.41 hacks document 146.gov www.happy tree friends.com dot document template free adobe auditions 1.5 o.w. coburn and law joseph pulitzer play.Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis- activating factor (APAF- 1). May attenuate inflammation by impairing NLRP1- inflammasome activation, hence CASP1 activation and IL1. B release (Pub. Med: 1. Bcl- 2 family proteins contribute to programmed cell death or apoptosis. It is a large protein family and all members contain at least one of four Bcl- 2 homology domains. Certain members (Bcl- 2, Bcl- XL and Mcl- 1) are antiapoptotic, whilst others (Bax, Bak, Bok) are proapoptotic. No data available for. Pharm. GKB "VIP" Summary . ![]() RNAdb sequence ontologies and. RNA Summary. for BCL2 Gene.
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